Defining the ClickOnce MIME Types (Magic xpa 2.x)
If the server where you are running your application does not have .NET installed on it, you need to define the following MIME type extensions on the server:
You do this in IIS as follows:
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Click on the MIME Types icon.
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If you don’t see the two MIME types listed there, then right-click on the screen and click Add.
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Enter the information in the Add MIME Type dialog box and click OK.